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Dr D. Collen, MD, PhD      I  Chairman and founder of ThromboGenics

Désiré Collen holds a MD degree and PhD degree in Chemistry from the University of Leuven, Belgium. Founder of ThromboGenics, he is currently Director of the Center for Molecular and Vascular Biology of the KULeuven, and the Center for Transgene Technology and Gene Therapy of the Flanders Interuniversity Institute for Biotechnology in Leuven, Belgium. He has received four honorary doctorates and several scientific awards including the Francqui Prize (Belgium). His team discovered and initially developed tPA, currently the most effective drug for thrombolytic therapy of acute myocardial infarction. Prof. Collen is a Non-Executive Director of Beta Cell NV.      I  top

Patrik De Haes, MD      I  Chief Operating Officer

Patrik De Haes has over 20 years of experience in the global health care industry, covering product development, marketing and general management. He joined from Roche in Switzerland, where he was Head of the Global Insulin Infusion business. Before that, Dr. De Haes was President and CEO of Disetronic Medical Systems Inc, a leading company in insulin infusion therapy, in Minneapolis, USA. At Sandoz Pharma (now Novartis) in Switzerland, he led the global development and commercialization of the first biotech product for that company. Dr. De Haes holds a degree in Medicine from the University of Leuven and a corporate MBA from the University of St. Thomas, Minneapolis, USA.      I  top

Chris Buyse      I  Chief Financial Officer

Chris Buyse brings to ThromboGenics 20 years experience in international company finance and in running and establishing best financial practice. He was previously CFO of the Belgian biotechnology company CropDesign, where he coordinated its acquisition by BASF in early 2007. Before this, Mr. Buyse was Finance Director of WorldCom/MCI Belux, a European subsidiary of one of the world’s largest telecom companies, and was CFO and interim CEO of Keyware Technologies, reporting to the President of the Board. In addition, he held several financial positions as financial controller and internal auditor at Spector Photo Group, Suez Lyonnaise des Eaux and Unilever.      I  top

Stuart Laermer, MSc, MBA      I  Chief Business Officer

Stuart Laermer is Chief Business Officer of ThromboGenics, responsible for the Company’s commercial activities, including partnering, licensing and business development. Mr. Laermer has more than 20 years of global experience in the commercialization of novel technologies. He was formerly Vice President, Business Development at Synthon Chiragenics and Physiome Sciences, where he was a member of the founding management team. He has also been Director, Business Development at Hoffmann-La Roche and Director, Biotechnology & Specialty Products at Fisher Scientific. Mr. Laermer received his MSc in Chemical Engineering from Columbia University, and MBA from New York University.      I  top

Steve Pakola, MD      I  Chief Medical Officer

Steve Pakola, who joined the Company in May 2000, is the Chief Medical Officer of ThromboGenics. Dr. Pakola is a licensed physician with extensive clinical trial experience, including over 11 years in pharma/biotech clinical development. Prior to joining the Company, Dr. Pakola was Associate Director, Cardiovascular Clinical Research, at Boehringer-Ingelheim Pharmaceuticals, where he served as global medical lead on the lipid-lowering development program, as well as U.S. medical lead for the direct thrombin inhibitor development program. Prior to Boehringer-Ingelheim, Dr. Pakola also served in senior-level clinical development positions at Quintiles Cardiovascular Therapeutics and Organon, Inc. Dr Pakola received his MD degree from the University of Pennsylvania.      I  top

Jean Marie Stassen, PhD      I  Senior Director, Research and Development

Jean Marie Stassen is Head of Research and Development and joined ThromboGenics in 2001. He is co-founder and member of the board of FlandersBio. Dr. Stassen was previously at Boehringer Ingelheim Pharma, Germany, where he served as a research project leader for the cardiovascular therapeutic area. As a preclinical expert, he was deeply involved in the European registration of the thrombolytic TNKase™ (Tenecteplase). Together with Prof. Collen, Dr. Stassen worked on the characterization of tPA and staphylokinase. He is author and co-author of more than 100 papers in peer-reviewed journals, and more than 250 patents and patent applications.      I  top

Patricia Young, PhD     I  Head Regulatory Affairs

Patricia Young is head of Regulatory Affairs for ThromboGenics and joined the Company in 2005. Dr. Young brings over 20 years of regulatory experience in the pharmaceutical industry, with more than a decade in executive management in organizations including Sanofi-Synthelabo, Covance and Boehringer Mannheim. Her regulatory career initiated in 1986 when she joined Pfizer in New York. Dr. Young earned a Ph.D. in clinical pharmacology from New York University. In her role as head of Regulatory Affairs for ThromboGenics, Dr. Young brings the commitment to implement some of the Company’s most important values: to ensure quality and safety of products that will offer reliable patient benefit.      I  top

Phil Challis      I  Head CMC

Phil Challis is head of chemistry, manufacturing and controls (CMC ). Phil brings over 20 years of experience in product development of biological entities. Phil has previously worked for UCB Pharma in a management role, and brings ThromboGenics experience in defining manufacturing strategy and planning late phase regulatory submissions. Phil has managed manufacturing programmes during early and late phase clinical trials and post commercialization. Phil has previously held key positions in product development functions at Lonza Biologics and Celltech, and brings valuable experience to ThromboGenics' strategic manufacturing policy.      I  top

Laurence Raemdonck      I  HR Manager

Laurence Raemdonck joined ThromboGenics as HR Manager in 2007. She is licensed in Germanic Philology and possesses a degree in Human Resources. She was previously employed in the telecom sector at Verizon Business. She has the responsibility for all areas related to human resources such as compensation, hiring, performance management, benefits, organization development, administration and training. As HR Manager, she is advocate for both the Company and its people, and therefore performs a constant balancing act in order to meet both needs successfully.      I  top
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