PRECLINICAL		CLINICAL
DRUG CANDIDATE	INDICATION		DISCOVERY	DEVELOPMENT	PHASE I	PHASE II	PHASE III
Microplasmin	Vitrectomy/Vitreoretinal traction
Microplasmin	Diabetic retinopathy (DME)
Microplasmin	Stroke
Staphylokinase	Acute myocardial infarction
Anti-factor VIII (TB-402)	Deep vein thrombosis
	Atrial fibrillation
Anti-PlGF (TB-403)	Cancer
	Age related macular degeneration
PlGF	Coronary artery disease, Peripheral arterial occlusive disease
Anti-VPAC	Thrombocytopenia
			Visual disorders   Cardiovascular disease   Cancer